Neuronal biomarkers and hippocampal volume in childhood-onset systemic lupus erythematosus

نویسندگان

  • Aline Lapa
  • Renata Barbosa
  • Mariana Postal
  • Nailu Sinicato
  • Fernando Cendes
  • Roberto Marini
  • Simone Appenzeller
چکیده

Introduction Hippocampal atrophy is associated with corticosteroid use and may be related to cognitive impairment in systemic lupus erythematosus (SLE). Some biomarkers associated with neuronal injury have been associated with neuropsychiatric SLE, but their roles in the pathogenesis and its validity and clinical applicability has not been studied in childhood-onset systemic lupus erythematosus (cSLE).

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عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2014